Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 8/20 | 0.56 |
| ▸ | FLT3 | P36888 | 5/20 | 0.56 |
| ▸ | SYK | P43405 | 10/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.46 |
| ▸ | JAK1 | P23458 | 2/20 | 0.46 |
| ▸ | JAK3 | P52333 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30839091 | 0.99 | JAK2 (0.57) | JAK2FLT3SYKPARP1JAK1 | |
| SCHEMBL30839088 | 0.93 | JAK2 (0.64) | JAK2FLT3SYKPARP1JAK1 | |
| SCHEMBL30839092 | 0.92 | FLT3 (0.61) | JAK2FLT3SYKPARP1MKNK1 | |
| SCHEMBL30839099 | 0.89 | JAK2 (0.51) | JAK2FLT3SYKPARP1JAK1 | |
| SCHEMBL29235730 | 0.84 | JAK2 (0.77) | JAK2FLT3JAK1JAK3 | |
| SCHEMBL29669890 | 0.84 | JAK2 (0.75) | JAK2FLT3SYKJAK1JAK3 | |
| SCHEMBL28437339 | 0.84 | JAK2 (0.75) | JAK2FLT3SYKJAK1JAK3 | |
| SCHEMBL29236023 | 0.83 | JAK2 (0.78) | JAK2FLT3JAK1JAK3 | |
| SCHEMBL29236031 | 0.79 | JAK2 (0.56) | JAK2FLT3PARP1JAK1JAK3 | |
| SCHEMBL21265727 | 0.78 | MKNK1 (0.53) | FLT3SYKPARP1MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005609-B | 2-Aminopyrimidine compound and application thereof | 沈阳药科大学 | 2025-06-17 | — | — | CN | claimed |
| CN-118005609-A | 2-Aminopyrimidine compound and application thereof | 沈阳药科大学 | 2024-05-10 | — | — | CN | claimed |
| CN-118005609-B | 2-Aminopyrimidine compound and application thereof | 沈阳药科大学 | 2025-06-17 | — | — | CN | disclosed |
| CN-118005609-A | 2-Aminopyrimidine compound and application thereof | 沈阳药科大学 | 2024-05-10 | — | — | CN | disclosed |