Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 8/20 | 0.61 |
| ▸ | JAK2 | O60674 | 6/20 | 0.61 |
| ▸ | PARP1 | P09874 | 1/20 | 0.59 |
| ▸ | SYK | P43405 | 5/20 | 0.52 |
| ▸ | CDK4 | P11802 | 1/20 | 0.51 |
| ▸ | CCND1 | P24385 | 1/20 | 0.51 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.51 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 3/20 | 0.49 |
| ▸ | ROS1 | P08922 | 3/20 | 0.49 |
| ▸ | EML4 | Q9HC35 | 3/20 | 0.49 |
| ▸ | ALK | Q9UM73 | 3/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30839091 | 0.93 | JAK2 (0.57) | FLT3JAK2PARP1SYK | |
| SCHEMBL30839100 | 0.92 | JAK2 (0.56) | FLT3JAK2PARP1SYKMKNK1 | |
| SCHEMBL30839099 | 0.90 | JAK2 (0.51) | FLT3JAK2PARP1SYKCDK4 | |
| SCHEMBL30839088 | 0.90 | JAK2 (0.64) | FLT3JAK2PARP1SYK | |
| SCHEMBL29235968 | 0.86 | JAK2 (0.85) | FLT3JAK2PARP1CDK4CCND1 | |
| SCHEMBL28437339 | 0.81 | JAK2 (0.75) | FLT3JAK2SYK | |
| SCHEMBL29669890 | 0.81 | JAK2 (0.75) | FLT3JAK2SYK | |
| SCHEMBL28322770 | 0.81 | JAK2 (0.71) | FLT3JAK2SYKCDK4CDK6 | |
| SCHEMBL29235848 | 0.81 | JAK2 (0.62) | FLT3JAK2PARP1CDK4CCND1 | |
| SCHEMBL29236023 | 0.79 | JAK2 (0.78) | FLT3JAK2CDK4CCND1CDK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005609-B | 2-Aminopyrimidine compound and application thereof | 沈阳药科大学 | 2025-06-17 | — | — | CN | claimed |
| CN-118005609-A | 2-Aminopyrimidine compound and application thereof | 沈阳药科大学 | 2024-05-10 | — | — | CN | claimed |
| CN-118005609-B | 2-Aminopyrimidine compound and application thereof | 沈阳药科大学 | 2025-06-17 | — | — | CN | disclosed |
| CN-118005609-A | 2-Aminopyrimidine compound and application thereof | 沈阳药科大学 | 2024-05-10 | — | — | CN | disclosed |