Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | METAP2 | P50579 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.36 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1461279 | 1.00 | BACE1 (0.48) | BACE1NOS1METAP2HTTCYP1A2 | |
| SCHEMBL46742 | 0.79 | BACE1 (0.55) | BACE1HTTPABPC1CDK5ALDH1A1 | |
| SCHEMBL1570789 | 0.79 | HTT (0.49) | BACE1NOS1METAP2HTTCYP1A2 | |
| SCHEMBL6844988 | 0.79 | BACE1 (0.46) | BACE1NOS1METAP2HTTCYP1A2 | |
| SCHEMBL29699229 | 0.79 | BACE1 (0.55) | BACE1HTTPABPC1CDK5ALDH1A1 | |
| SCHEMBL1517340 | 0.79 | BACE1 (0.46) | BACE1NOS1METAP2HTTCYP1A2 | |
| SCHEMBL1570979 | 0.79 | BACE1 (0.46) | BACE1NOS1METAP2HTTCYP1A2 | |
| SCHEMBL11905848 | 0.79 | MAPT (0.43) | HTTCYP1A2CDK9CDK5CLK4 | |
| SCHEMBL27902366 | 0.79 | CYP1A2 (0.48) | BACE1HTTCYP1A2CYP2A6ALDH1A1 | |
| SCHEMBL18769916 | 0.79 | HTR3A (0.47) | BACE1NOS1CYP2A6ALDH1A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117820345-A | Blue light material based on dibenzofuran-aza condensed ring, preparation and application thereof | 山西大同大学 | 2024-04-05 | — | — | CN | disclosed |