SCHEMBL30839645

SCHEMBL30839645

O=C(O)C[C@@H]1NC(=O)[C@@H]2CCCN2C1=O

nearest known ligand 0.60

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.52
▸ HDAC4 P56524 15/20 0.49
▸ HDAC1 Q13547 13/20 0.49
▸ HDAC6 Q9UBN7 8/20 0.48
▸ HDAC3 O15379 3/20 0.48
▸ HDAC7 Q8WUI4 3/20 0.48
▸ HDAC2 Q92769 3/20 0.48
▸ HDAC10 Q969S8 3/20 0.48
▸ HDAC11 Q96DB2 3/20 0.48
▸ HDAC8 Q9BY41 3/20 0.48
▸ HDAC9 Q9UKV0 3/20 0.48
▸ HDAC5 Q9UQL6 3/20 0.48
▸ KLHL20 Q9Y2M5 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14952755 0.87 SMN1; SMN2 (0.51) SMN1; SMN2HDAC4HDAC1HDAC6HDAC3
SCHEMBL14952768 0.85 HDAC4 (0.56) SMN1; SMN2HDAC4HDAC1HDAC6HDAC3
SCHEMBL14952791 0.83 SMN1; SMN2 (0.56) SMN1; SMN2HDAC4HDAC1HDAC6HDAC3
SCHEMBL30281500 0.83 SMN1; SMN2 (0.56) SMN1; SMN2HDAC4HDAC1HDAC6HDAC3
SCHEMBL14952813 0.81 SMN1; SMN2 (0.57) SMN1; SMN2HDAC4HDAC1HDAC6HDAC3
SCHEMBL4405235 0.81 SMN1; SMN2 (0.57) SMN1; SMN2HDAC4HDAC1HDAC6HDAC3
SCHEMBL4402054 0.81 SMN1; SMN2 (0.57) SMN1; SMN2HDAC4HDAC1HDAC6HDAC3
SCHEMBL12228285 0.81 SMN1; SMN2 (0.57) SMN1; SMN2HDAC4HDAC1HDAC6HDAC3
SCHEMBL14952812 0.78 HDAC4 (0.55) SMN1; SMN2HDAC4HDAC1HDAC6HDAC3
SCHEMBL14952806 0.78 SMN1; SMN2 (0.58) SMN1; SMN2HDAC4HDAC1HDAC6HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4594325-A1 PEG-MODIFIED CYCLIC DIPEPTIDES Novmetapharma Co., Ltd. (KR) 2025-08-06 — — EP claimed
US-20240140955-A1 PEG-MODIFIED CYCLIC DIPEPTIDES NOVMETAPHARMA CO., LTD. (KR) 2024-05-02 — — US claimed
WO-2024069524-A1 PEG-MODIFIED CYCLIC DIPEPTIDES NOVMETAPHARMA CO., LTD. (KR) 2024-04-04 — — WO claimed
EP-4594325-A1 PEG-MODIFIED CYCLIC DIPEPTIDES Novmetapharma Co., Ltd. (KR) 2025-08-06 — — EP disclosed
US-20240140955-A1 PEG-MODIFIED CYCLIC DIPEPTIDES NOVMETAPHARMA CO., LTD. (KR) 2024-05-02 — — US disclosed
WO-2024069524-A1 PEG-MODIFIED CYCLIC DIPEPTIDES NOVMETAPHARMA CO., LTD. (KR) 2024-04-04 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240140955-A1 PEG-MODIFIED CYCLIC DIPEPTIDES LNPEP, ANPEP, DNPEP SMN1; SMN2 4537/4885HDAC4 1691/4885HDAC1 506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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