Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 5/20 | 0.38 |
| ▸ | CSF1R | P07333 | 5/20 | 0.38 |
| ▸ | CDK4 | P11802 | 5/20 | 0.38 |
| ▸ | CDK6 | Q00534 | 5/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK7 | P50613 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | CCNH | P51946 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 3/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30011461 | 0.78 | ATM (0.42) | PIK3CDCSF1RCDK4CDK6SYK | |
| SCHEMBL30839669 | 0.76 | TLR9 (0.37) | CSF1RCDK4CDK6SYKCHEK2 | |
| SCHEMBL30839670 | 0.75 | ATM (0.39) | PIK3CDATMPIK3CAMTOR | |
| SCHEMBL30012532 | 0.70 | ATM (0.41) | SYKATMPIK3CAMTOR | |
| SCHEMBL30839640 | 0.70 | ATM (0.41) | SYKATMPIK3CAMTOR | |
| SCHEMBL30011050 | 0.70 | MTOR (0.41) | PIK3CDCSF1RCDK4CDK6SYK | |
| SCHEMBL23093828 | 0.66 | PRKDC (0.59) | PIK3CDCSF1RCDK4CDK6ATM | |
| SCHEMBL21541787 | 0.64 | PRKDC (0.61) | ATMMTOR | |
| SCHEMBL30012314 | 0.64 | ATM (0.48) | PIK3CDCSF1RCDK4CDK6KDM1A | |
| SCHEMBL29217588 | 0.64 | ATM (0.48) | PIK3CDCSF1RCDK4CDK6KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114026097-B | Substituted pyrazoloquinazolinone compounds and uses thereof | 上海瑛派药业有限公司 | 2024-02-23 | — | — | CN | disclosed |