Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.37 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | MTOR | P42345 | 6/20 | 0.37 |
| ▸ | CSF1R | P07333 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 3/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | ATR | Q13535 | 2/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30012567 | 0.77 | MTOR (0.45) | TLR9TLR8TLR7MTORCSF1R | |
| SCHEMBL29217578 | 0.77 | MTOR (0.45) | TLR9TLR8TLR7MTORCSF1R | |
| SCHEMBL30839660 | 0.76 | PIK3CD (0.38) | MTORCSF1RCDK4CDK6ATM | |
| SCHEMBL21267237 | 0.67 | CSF1R (0.41) | CSF1RCDK4CDK6PDE3BPDE3A | |
| SCHEMBL30012314 | 0.67 | ATM (0.48) | TLR9TLR8TLR7MTORCSF1R | |
| SCHEMBL29217588 | 0.67 | ATM (0.48) | TLR9TLR8TLR7MTORCSF1R | |
| SCHEMBL23294917 | 0.66 | PIK3CA (0.36) | MTORCSF1RCDK4CDK6PDE3B | |
| SCHEMBL29217613 | 0.66 | ATM (0.45) | TLR9TLR8TLR7MTORATM | |
| SCHEMBL30011984 | 0.66 | ATM (0.45) | TLR9TLR8TLR7MTORATM | |
| SCHEMBL20374410 | 0.65 | HSD11B1 (0.43) | CSF1RCDK4CDK6SYKPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114026097-B | Substituted pyrazoloquinazolinone compounds and uses thereof | 上海瑛派药业有限公司 | 2024-02-23 | — | — | CN | disclosed |