Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FSCN1 | Q16658 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6351465 | 0.87 | NR1H4 (0.40) | FSCN1NR1H4CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL13574289 | 0.85 | GAA (0.41) | NR1H4CYP3A4CYP2C9CYP2C19NR1H2 | |
| SCHEMBL30369795 | 0.84 | ABL1 (0.39) | CYP2C9CYP2C19NR1H2TSHRALDH1A1 | |
| SCHEMBL18157855 | 0.84 | ABL1 (0.39) | CYP2C9CYP2C19NR1H2TSHRALDH1A1 | |
| SCHEMBL30370098 | 0.82 | ABL1 (0.37) | NR1H2BRD4PAX8MAPT | |
| SCHEMBL18157853 | 0.82 | ABL1 (0.37) | NR1H2BRD4PAX8MAPT | |
| SCHEMBL15156638 | 0.81 | NR1H2 (0.37) | CYP3A4NR1H2TSHRALDH1A1CASP1 | |
| SCHEMBL27270154 | 0.80 | NR1H4 (0.36) | NR1H4CYP3A4CYP2C9CYP2C19CHRM2 | |
| SCHEMBL18157856 | 0.79 | NR1H2 (0.36) | HTR2CNR1H2ALDH1A1BRD4PAX8 | |
| SCHEMBL27267299 | 0.79 | NR1H4 (0.36) | NR1H4CYP3A4CYP2C9CYP2C19CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119948028-A | Condensed-cyclic compound, pharmaceutical composition and application thereof | 海南先声再明医药股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| WO-2024067792-A1 | FUSED RING COMPOUND, PHARMACEUTICAL COMPOSITION, AND USE THEREOF | 海南先声再明医药股份有限公司 | 2024-04-04 | — | — | WO | disclosed |