Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 3/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23520755 | 0.83 | KMT2A (0.39) | KMT2AMEN1ACHECES2NPSR1 | |
| SCHEMBL23520759 | 0.83 | KMT2A (0.39) | KMT2AMEN1ACHECES2NPSR1 | |
| SCHEMBL26375683 | 0.81 | ACSS2 (0.40) | KMT2AMEN1ACHENPSR1POLB | |
| SCHEMBL25077732 | 0.81 | ACSS2 (0.40) | KMT2AMEN1ACHENPSR1POLB | |
| SCHEMBL25839658 | 0.81 | ACSS2 (0.40) | KMT2AMEN1ACHENPSR1POLB | |
| SCHEMBL30454833 | 0.81 | ACSS2 (0.40) | KMT2AMEN1ACHENPSR1POLB | |
| SCHEMBL31463895 | 0.81 | ACSS2 (0.40) | KMT2AMEN1ACHENPSR1POLB | |
| SCHEMBL29945770 | 0.81 | ACSS2 (0.40) | KMT2AMEN1ACHENPSR1POLB | |
| SCHEMBL22321401 | 0.80 | KMT2A (0.52) | KMT2AMEN1CES2NPSR1POLB | |
| SCHEMBL21133184 | 0.80 | KMT2A (0.43) | KMT2AMEN1ACHECES2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836278-A | SOS1 inhibitor, preparation method and application thereof | 上海海和药物研究开发股份有限公司 | 2024-04-05 | — | — | CN | disclosed |