Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 9/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM6B | O15054 | 1/20 | 0.43 |
| ▸ | KDM6A | O15550 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30842481 | 0.92 | NPC1 (0.51) | NPC1MAPTKDM4EALDH1A1PTGS2 | |
| SCHEMBL25192531 | 0.80 | NPC1 (0.68) | NPC1MAPTKDM4EALDH1A1PTGS2 | |
| SCHEMBL30842503 | 0.80 | NPC1 (0.68) | NPC1MAPTKDM4EALDH1A1PTGS2 | |
| SCHEMBL30730423 | 0.78 | TUBB4A (0.44) | MAPTKDM4EALDH1A1TP53HSD17B10 | |
| SCHEMBL29149091 | 0.78 | TUBB4A (0.44) | MAPTKDM4EALDH1A1TP53HSD17B10 | |
| SCHEMBL30959734 | 0.77 | KDM6B (0.56) | NPC1MAPTKDM4EALDH1A1PTGS2 | |
| SCHEMBL8964777 | 0.76 | KDM6B (0.61) | NPC1MAPTKDM4EALDH1A1PTGS2 | |
| SCHEMBL31164530 | 0.75 | NPC1 (0.61) | NPC1MAPTKDM4EALDH1A1PTGS2 | |
| SCHEMBL31010852 | 0.75 | MAPT (0.45) | NPC1MAPTKDM4EALDH1A1HPGD | |
| SCHEMBL25195617 | 0.75 | NPC1 (0.61) | NPC1MAPTKDM4EALDH1A1PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118317952-A | Heterocyclic substituted phenol derivatives, process for their preparation and their use | 上海泽德曼医药科技有限公司 | 2024-07-09 | — | — | CN | disclosed |
| WO-2024078372-A1 | HETEROCYCLIC SUBSTITUTED PHENOL DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海泽德曼医药科技有限公司 | 2024-04-18 | — | — | WO | disclosed |