Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 2/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | BCR | P11274 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SERPINE1 | P05121 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.40 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21458220 | 1.00 | EPHX2 (0.45) | EPHX2PPARAABL1BCRLMNA | |
| SCHEMBL21458301 | 0.89 | EPHX2 (0.48) | EPHX2PPARAABL1BCRLMNA | |
| SCHEMBL30843258 | 0.89 | EPHX2 (0.48) | EPHX2PPARAABL1BCRLMNA | |
| SCHEMBL21482082 | 0.86 | KDM4E (0.39) | LMNAKDM4ECHRM1 | |
| SCHEMBL26601878 | 0.86 | L3MBTL1 (0.46) | LMNAKDM4ECHRM1 | |
| SCHEMBL21458237 | 0.85 | HSP90AA1 (0.39) | KDM4ECHRM1 | |
| SCHEMBL30843268 | 0.85 | HSP90AA1 (0.39) | KDM4ECHRM1 | |
| SCHEMBL30843266 | 0.83 | CHRM1 (0.47) | SERPINE1KDM4ECHRM1 | |
| SCHEMBL21458142 | 0.83 | CHRM1 (0.47) | SERPINE1KDM4ECHRM1 | |
| SCHEMBL21481836 | 0.83 | NPC1 (0.43) | AMPD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3781550-B1 | BICYCLIC CARBOXAMIDES AND METHODS OF USE THEREOF | TEMPEST THERAPEUTICS INC (US) | 2024-10-30 | — | — | EP | disclosed |
| CN-112313208-B | Bicyclic carboxamides and methods of use thereof | 泰普斯特医疗公司 | 2024-04-19 | — | — | CN | disclosed |