Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.73 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.58 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.58 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.53 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.53 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | EDNRA | P25101 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTR2B | P41595 | 1/20 | 0.53 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30844554 | 0.89 | ACHE (0.72) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL27423689 | 0.89 | ACHE (0.72) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL13539708 | 0.88 | ACHE (0.74) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL30844566 | 0.88 | ACHE (0.74) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL14305060 | 0.88 | ACHE (0.74) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL13539702 | 0.88 | ACHE (0.73) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL13539738 | 0.88 | ACHE (0.73) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL13539718 | 0.86 | ACHE (0.72) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL4771597 | 0.86 | ACHE (0.70) | ACHEAGTR1LTB4R2ABCC3ABCC4 | |
| SCHEMBL13539727 | 0.85 | ACHE (0.69) | ACHEAGTR1LTB4R2ABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836294-A | Biological antagonist containing aromatic ring, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |