Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PPIA | P62937 | 2/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | RXRA | P19793 | 1/20 | 0.47 |
| ▸ | RXRB | P28702 | 1/20 | 0.47 |
| ▸ | RXRG | P48443 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2394250 | 1.00 | SMN1; SMN2 (0.51) | SMN1; SMN2NPC1RAB9AHPGDPPIA | |
| SCHEMBL20482380 | 0.91 | KMT2A (0.57) | SMN1; SMN2NPC1RAB9AHPGDSMPD1 | |
| SCHEMBL4403626 | 0.88 | SMN1; SMN2 (0.61) | SMN1; SMN2NPC1RAB9AHPGDPPIA | |
| SCHEMBL14914125 | 0.86 | SMPD1 (0.59) | SMN1; SMN2NPC1RAB9AHPGDPPIA | |
| SCHEMBL28877494 | 0.85 | MEN1 (0.54) | SMN1; SMN2NPC1RAB9AHPGDPPIA | |
| SCHEMBL4279981 | 0.85 | HSD17B10 (0.61) | SMN1; SMN2NPC1RAB9AHPGDPPIA | |
| SCHEMBL3654864 | 0.84 | HSD17B2 (0.56) | HSD17B2 | |
| SCHEMBL16055886 | 0.84 | SMN1; SMN2 (0.54) | SMN1; SMN2NPC1RAB9AHPGDPPIA | |
| SCHEMBL340393 | 0.84 | SMN1; SMN2 (0.72) | SMN1; SMN2NPC1RAB9AHPGDSMPD1 | |
| SCHEMBL28877558 | 0.84 | MCL1 (0.56) | SMN1; SMN2NPC1RAB9AHPGDPPIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836294-A | Biological antagonist containing aromatic ring, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |