Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT8 | Q16880 | 15/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21813377 | 1.00 | UGT8 (0.49) | UGT8KDM4EOPRK1HRH3SMPD3 | |
| SCHEMBL21814080 | 0.86 | UGT8 (0.64) | UGT8KDM4E | |
| SCHEMBL21813543 | 0.86 | UGT8 (0.66) | UGT8KDM4E | |
| SCHEMBL30845146 | 0.86 | UGT8 (0.64) | UGT8KDM4E | |
| SCHEMBL21813832 | 0.79 | UGT8 (0.76) | UGT8 | |
| SCHEMBL21814077 | 0.77 | UGT8 (0.62) | UGT8 | |
| SCHEMBL21813991 | 0.77 | UGT8 (0.80) | UGT8 | |
| SCHEMBL21813885 | 0.76 | UGT8 (0.66) | UGT8KDM4E | |
| SCHEMBL21813611 | 0.75 | UGT8 (0.71) | UGT8 | |
| SCHEMBL21813383 | 0.74 | UGT8 (0.64) | UGT8KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | claimed |
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | disclosed |