Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT8 | Q16880 | 13/20 | 0.64 |
| ▸ | ACACB | O00763 | 4/20 | 0.42 |
| ▸ | ACACA | Q13085 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NAPEPLD | Q6IQ20 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21814080 | 1.00 | UGT8 (0.64) | UGT8ACACBACACAKDM4ENAPEPLD | |
| SCHEMBL21813753 | 0.87 | UGT8 (0.83) | UGT8KDM4E | |
| SCHEMBL21813377 | 0.86 | UGT8 (0.49) | UGT8KDM4E | |
| SCHEMBL30844944 | 0.86 | UGT8 (0.49) | UGT8KDM4E | |
| SCHEMBL21862463 | 0.80 | UGT8 (0.78) | UGT8ACACBACACA | |
| SCHEMBL21813589 | 0.79 | UGT8 (0.83) | UGT8 | |
| SCHEMBL21862127 | 0.78 | UGT8 (1.00) | UGT8 | |
| Hydrochloric Acid SCHEMBL21814166 | 0.77 | UGT8 (0.98) | UGT8 | |
| SCHEMBL21813832 | 0.77 | UGT8 (0.76) | UGT8 | |
| Hydrochloric Acid SCHEMBL21814153 | 0.77 | UGT8 (0.88) | UGT8ACACBACACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | claimed |
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | disclosed |