Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT8 | Q16880 | 19/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21814002 | 1.00 | UGT8 (0.77) | UGT8KDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL21813342 | 0.90 | UGT8 (0.76) | UGT8KDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL21814038 | 0.90 | UGT8 (0.76) | UGT8KDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL21813441 | 0.88 | UGT8 (0.74) | UGT8KDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL21813732 | 0.88 | UGT8 (0.77) | UGT8KDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL21814130 | 0.88 | UGT8 (0.74) | UGT8KDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL21813969 | 0.87 | UGT8 (0.73) | UGT8 | |
| SCHEMBL21814139 | 0.87 | UGT8 (1.00) | UGT8 | |
| SCHEMBL30844976 | 0.87 | UGT8 (1.00) | UGT8 | |
| SCHEMBL21813359 | 0.87 | UGT8 (0.74) | UGT8KDM4EALDH1A1SMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | claimed |
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | disclosed |