Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT8 | Q16880 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30845413 | 0.83 | ALDH1A1 (0.47) | UGT8ALDH1A1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL30845050 | 0.74 | UGT8 (0.72) | UGT8CYP11B2 | |
| SCHEMBL21813748 | 0.74 | UGT8 (0.72) | UGT8CYP11B2 | |
| SCHEMBL21813409 | 0.72 | UGT8 (0.47) | UGT8ALDH1A1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL30845392 | 0.71 | UGT8 (0.43) | UGT8ALDH1A1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL21813973 | 0.71 | UGT8 (0.69) | UGT8ALDH1A1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL30845007 | 0.71 | UGT8 (0.69) | UGT8ALDH1A1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL30845419 | 0.70 | UGT8 (0.71) | UGT8CYP11B2 | |
| SCHEMBL21813746 | 0.68 | UGT8 (0.68) | UGT8ALDH1A1SMN1; SMN2KDM4ETDP1 | |
| SCHEMBL21814139 | 0.66 | UGT8 (1.00) | UGT8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | disclosed |