Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | F2RL1 | P55085 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21813993 | 0.81 | ALDH1A1 (0.43) | ALDH1A1CHRM5CHRM3KMT2AHTT | |
| SCHEMBL2395196 | 0.80 | EPHX2 (0.40) | ALDH1A1CHRM3EPHX2GPR119KMT2A | |
| SCHEMBL21828490 | 0.80 | SMN1; SMN2 (0.41) | ALDH1A1CHRM5CHRM3KMT2AMEN1 | |
| SCHEMBL30845396 | 0.79 | ALDH1A1 (0.57) | ALDH1A1CHRM5CHRM3EPHX2MAPT | |
| SCHEMBL25698961 | 0.78 | CHRM1 (0.43) | ALDH1A1EPHX2GPR119KMT2AMEN1 | |
| SCHEMBL22346651 | 0.76 | USP2 (0.41) | ALDH1A1EPHX2GPR119KMT2AMEN1 | |
| SCHEMBL24069318 | 0.74 | USP2 (0.39) | ALDH1A1EPHX2GPR119KMT2AMEN1 | |
| SCHEMBL17946329 | 0.74 | USP2 (0.39) | ALDH1A1EPHX2GPR119KMT2AMEN1 | |
| SCHEMBL17789628 | 0.73 | USP2 (0.42) | ALDH1A1EPHX2GPR119KMT2AMEN1 | |
| SCHEMBL18502954 | 0.72 | ALDH1A1 (0.39) | ALDH1A1CHRM5CHRM3EPHX2GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113423711-B | Thieno [3,2-B ] pyridine derivatives as UDP glycosyltransferase inhibitors and methods of use thereof | 建新公司 | 2024-03-15 | — | — | CN | disclosed |