Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RET | P07949 | 17/20 | 0.43 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21530427 | 1.00 | RET (0.43) | RETMAP3K5NPC1RAB9ATSHR | |
| SCHEMBL21530442 | 0.78 | MAP3K5 (0.43) | MAP3K5NPC1RAB9A | |
| SCHEMBL30845495 | 0.78 | MAP3K5 (0.43) | MAP3K5NPC1RAB9A | |
| SCHEMBL21530435 | 0.75 | MAP3K5 (0.50) | RETMAP3K5NPC1RAB9ATSHR | |
| SCHEMBL30845493 | 0.75 | MAP3K5 (0.50) | RETMAP3K5NPC1RAB9ATSHR | |
| SCHEMBL24638845 | 0.70 | RET (0.42) | RETNPC1RAB9ATSHR | |
| SCHEMBL21530424 | 0.70 | MAP3K5 (0.41) | RETMAP3K5NPC1RAB9ATSHR | |
| SCHEMBL30605718 | 0.69 | STAT3 (0.52) | RETNPC1RAB9A | |
| SCHEMBL11843303 | 0.69 | STAT3 (0.43) | RETNPC1RAB9A | |
| Hydrochloric Acid SCHEMBL30605737 | 0.68 | STAT3 (0.51) | RETNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112312905-B | Tetrazole-containing inhibitors of apoptosis signal-regulating kinase 1 and methods of use thereof | 英安塔制药有限公司 | 2024-03-15 | — | — | CN | disclosed |