SCHEMBL3084595

SCHEMBL3084595

c1ccc2c(c1)ncn2CCSSCCn1cnc2ccccc21

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.75
▸ LMNA P02545 7/20 0.62
▸ SMN1; SMN2 Q16637 7/20 0.62
▸ HTT P42858 4/20 0.62
▸ EGLN3 Q9H6Z9 1/20 0.58
▸ L3MBTL1 Q9Y468 1/20 0.58
▸ CYP11B1 P15538 3/20 0.56
▸ CYP11B2 P19099 3/20 0.56
▸ TNF P01375 1/20 0.56
▸ TSHR P16473 2/20 0.55
▸ NPSR1 Q6W5P4 1/20 0.55
▸ PKM P14618 1/20 0.55
▸ ALOX15 P16050 1/20 0.55
▸ RAB9A P51151 2/20 0.53
▸ GAA P10253 1/20 0.53
▸ MAPK1 P28482 1/20 0.51
▸ GGPS1 O95749 1/20 0.51
▸ FDPS P14324 1/20 0.51
▸ MAPT P10636 2/20 0.51
▸ NPC1 O15118 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32660139 1.00 TDP1 (0.75) TDP1LMNASMN1; SMN2HTTEGLN3
SCHEMBL3069742 0.89 TDP1 (0.75) TDP1LMNASMN1; SMN2HTTEGLN3
SCHEMBL6442808 0.86 TDP1 (1.00) TDP1LMNASMN1; SMN2HTTEGLN3
SCHEMBL13870066 0.86 TDP1 (0.70) TDP1LMNASMN1; SMN2HTTEGLN3
SCHEMBL3065318 0.85 TDP1 (0.74) TDP1LMNASMN1; SMN2HTTEGLN3
SCHEMBL32660136 0.85 TDP1 (0.74) TDP1LMNASMN1; SMN2HTTEGLN3
SCHEMBL9814242 0.82 TDP1 (0.84) TDP1LMNASMN1; SMN2HTTEGLN3
SCHEMBL30294105 0.82 TDP1 (0.84) TDP1LMNASMN1; SMN2HTTEGLN3
SCHEMBL3161153 0.82 TDP1 (0.84) TDP1LMNASMN1; SMN2HTTEGLN3
Ammonia Solution, Strong SCHEMBL7100443 0.81 TDP1 (0.81) TDP1LMNASMN1; SMN2HTTEGLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9546232-B2 Rubber composition, and pneumatic tire using same BRIDGESTONE CORPORATION (JP) 2017-01-17 — — US disclosed
US-9546232-B2 Rubber composition, and pneumatic tire using same BRIDGESTONE CORPORATION (JP) 2017-01-17 — — US disclosed
US-20150353657-A1 RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME OTSUKA CHEMICAL CO., LTD. (JP) 2015-12-10 — — US disclosed
US-20150353657-A1 RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME OTSUKA CHEMICAL CO., LTD. (JP) 2015-12-10 — — US disclosed
EP-2952541-A1 RUBBER COMPOSITION, AND PNEUMATIC TIRE USING SAME Bridgestone Corporation (JP) 2015-12-09 — — EP disclosed
US-7833331-B2 Non-toxic corrosion-protection pigments based on cobalt UNIVERSITY OF DAYTON (US) 2010-11-16 — — US disclosed
US-7789958-B2 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON (US) 2010-09-07 — — US disclosed
US-20090163628-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON COBALT STURGILL JEFFREY ALLEN 2009-06-25 — — US disclosed
US-7422793-B2 Non-toxic corrosion-protection rinses and seals based on rare earth elements UNIVERSITY OF DAYTON (US) 2008-09-09 — — US disclosed
US-7294211-B2 Non-toxic corrosion-protection conversion coats based on cobalt UNIVERSITY OF DAYTON (US) 2007-11-13 — — US disclosed
US-7235142-B2 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON (US) 2007-06-26 — — US disclosed
EP-1472319-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2004-11-03 — — EP disclosed
WO-2004065305-A1 NON-TOXIC CORROSION-PROTECTION PIGMENTS BASED ON MANGANESE UNIVERSITY OF DAYTON (US) 2004-08-05 — — WO disclosed
US-20040104377-A1 Non-toxic corrosion-protection pigments based on rare earth elements UNIVERSITY OF DAYTON 2004-06-03 — — US disclosed
US-20040016910-A1 Non-toxic corrosion-protection rinses and seals based on rare earth elements DAYTON, UNIVERSITY OF 2004-01-29 — — US disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 — — US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 — — US disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 — — US disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 — — WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 — — WO disclosed
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