Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.48 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.46 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.39 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.39 |
| ▸ | KIT | P10721 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27119198 | 1.00 | EIF2AK3 (0.48) | EIF2AK3PTGES2SLC40A1GLO1KIT | |
| SCHEMBL27123171 | 0.88 | EIF2AK3 (0.41) | EIF2AK3PTGES2SLC40A1GLO1LMNA | |
| SCHEMBL30846311 | 0.87 | PTGES2 (0.43) | EIF2AK3PTGES2SLC40A1GLO1LMNA | |
| SCHEMBL27118019 | 0.87 | PTGES2 (0.43) | EIF2AK3PTGES2SLC40A1GLO1LMNA | |
| SCHEMBL30846341 | 0.87 | SLC40A1 (0.41) | SLC40A1GLO1KITLMNAPIK3CA | |
| SCHEMBL27118142 | 0.87 | SLC40A1 (0.41) | SLC40A1GLO1KITLMNAPIK3CA | |
| SCHEMBL30846288 | 0.86 | GAA (0.38) | EIF2AK3SLC40A1GLO1LMNAPIK3CA | |
| SCHEMBL27118277 | 0.86 | GAA (0.38) | EIF2AK3SLC40A1GLO1LMNAPIK3CA | |
| SCHEMBL27119245 | 0.86 | GAA (0.48) | SLC40A1LMNAPIK3CAMAPK1 | |
| SCHEMBL30846276 | 0.86 | SLC40A1 (0.40) | EIF2AK3SLC40A1GLO1LMNAPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044344-A1 | PYRIDINYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY | HOTSPOT THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |