Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 14/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CKS1B | P61024 | 1/20 | 0.39 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30846413 | 1.00 | SLC40A1 (0.46) | SLC40A1KMT2ATDP1MAPTMITF | |
| SCHEMBL27118191 | 1.00 | SLC40A1 (0.46) | SLC40A1KMT2ATDP1MAPTMITF | |
| SCHEMBL27118194 | 0.89 | PIK3CA (0.40) | SLC40A1GLO1PIK3CA | |
| SCHEMBL30846391 | 0.89 | PTGES2 (0.43) | SLC40A1GLO1PIK3CAGAA | |
| SCHEMBL27118083 | 0.89 | PTGES2 (0.43) | SLC40A1GLO1PIK3CAGAA | |
| SCHEMBL30846237 | 0.89 | SLC40A1 (0.41) | SLC40A1KMT2ATDP1MAPTMITF | |
| SCHEMBL30846482 | 0.89 | PIK3CA (0.40) | SLC40A1GLO1PIK3CA | |
| SCHEMBL27118278 | 0.89 | SLC40A1 (0.41) | SLC40A1KMT2ATDP1MAPTMITF | |
| SCHEMBL30846465 | 0.88 | SLC40A1 (0.40) | SLC40A1KMT2ATDP1MAPTMITF | |
| SCHEMBL27118193 | 0.88 | SLC40A1 (0.40) | SLC40A1KMT2ATDP1MAPTMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044344-A1 | PYRIDINYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY | HOTSPOT THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |