Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 6/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27125949 | 1.00 | SLC40A1 (0.41) | SLC40A1PTPN11SLC16A3SCN9AMMP2 | |
| SCHEMBL27126476 | 0.87 | SLC40A1 (0.41) | SLC40A1SLC16A3MMP2LMNAMAPK1 | |
| SCHEMBL30846365 | 0.87 | SLC40A1 (0.41) | SLC40A1SLC16A3MMP2LMNAMAPK1 | |
| SCHEMBL27125948 | 0.84 | TDP1 (0.41) | SLC40A1PTPN11SLC16A3SCN9AMMP2 | |
| SCHEMBL30846168 | 0.76 | GAA (0.55) | SLC40A1PTPN11SCN9ALMNAMAPK1 | |
| SCHEMBL27125947 | 0.76 | GAA (0.55) | SLC40A1PTPN11SCN9ALMNAMAPK1 | |
| SCHEMBL30846335 | 0.74 | PIK3CG (0.35) | SLC40A1SLC16A3SCN9ATDP1 | |
| SCHEMBL27125155 | 0.74 | PIK3CG (0.35) | SLC40A1SLC16A3SCN9ATDP1 | |
| SCHEMBL30846164 | 0.72 | SLC40A1 (0.42) | SLC40A1SCN9AEIF2AK3 | |
| SCHEMBL30846218 | 0.72 | PIK3CA (0.32) | LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044344-A1 | PYRIDINYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY | HOTSPOT THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |