Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | SLC40A1 | Q9NP59 | 6/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.36 |
| ▸ | EIF2AK3 | Q9NZJ5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27117954 | 1.00 | PIK3CD (0.39) | PIK3CDPIK3CBMTORPIK3CGSLC40A1 | |
| SCHEMBL27118386 | 0.87 | PTPN11 (0.40) | MTORSLC40A1EIF2AK3PTPN11 | |
| SCHEMBL27122988 | 0.87 | SLC40A1 (0.37) | SLC40A1EIF2AK3ALDH1A1OPRK1HTT | |
| SCHEMBL27118195 | 0.86 | SLC40A1 (0.40) | SLC40A1EIF2AK3ALDH1A1OPRK1HTT | |
| SCHEMBL27118078 | 0.86 | SLC40A1 (0.42) | SLC40A1ALDH1A1OPRK1HTTNPSR1 | |
| SCHEMBL27118193 | 0.86 | SLC40A1 (0.40) | SLC40A1EIF2AK3ALDH1A1OPRK1HTT | |
| SCHEMBL30846306 | 0.86 | SLC40A1 (0.42) | SLC40A1ALDH1A1OPRK1HTTNPSR1 | |
| SCHEMBL30846465 | 0.86 | SLC40A1 (0.40) | SLC40A1EIF2AK3ALDH1A1OPRK1HTT | |
| SCHEMBL30846276 | 0.86 | SLC40A1 (0.40) | SLC40A1EIF2AK3ALDH1A1OPRK1HTT | |
| SCHEMBL30846443 | 0.85 | SLC40A1 (0.48) | SLC40A1BRD4ALDH1A1OPRK1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044344-A1 | PYRIDINYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY | HOTSPOT THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |