Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.57 |
| ▸ | EGFR | P00533 | 1/20 | 0.57 |
| ▸ | BCR | P11274 | 1/20 | 0.57 |
| ▸ | SRC | P12931 | 1/20 | 0.57 |
| ▸ | PRKCA | P17252 | 1/20 | 0.57 |
| ▸ | PRKACA | P17612 | 1/20 | 0.57 |
| ▸ | PRKACG | P22612 | 1/20 | 0.57 |
| ▸ | PRKACB | P22694 | 1/20 | 0.57 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.57 |
| ▸ | CDK2 | P24941 | 9/20 | 0.55 |
| ▸ | GSK3B | P49841 | 7/20 | 0.55 |
| ▸ | AURKA | O14965 | 2/20 | 0.54 |
| ▸ | CDK4 | P11802 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.52 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.52 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
| ▸ | CLK2 | P49760 | 1/20 | 0.52 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.52 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.51 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27109944 | 1.00 | ABL1 (0.57) | ABL1EGFRBCRSRCPRKCA | |
| SCHEMBL13051119 | 0.86 | ABL1 (0.55) | ABL1EGFRBCRSRCPRKCA | |
| SCHEMBL13051120 | 0.84 | ABL1 (0.58) | ABL1EGFRBCRSRCPRKCA | |
| SCHEMBL2542944 | 0.84 | CCNB2 (0.67) | ABL1EGFRBCRSRCPRKCA | |
| SCHEMBL13051126 | 0.82 | DYRK1B (0.60) | ABL1EGFRBCRSRCPRKCA | |
| SCHEMBL13051121 | 0.82 | CDK2 (0.56) | ABL1EGFRBCRSRCPRKCA | |
| SCHEMBL13051124 | 0.82 | EGFR (0.59) | ABL1EGFRBCRSRCPRKCA | |
| SCHEMBL3247348 | 0.79 | AURKA (0.58) | CDK2GSK3BAURKACDK4DYRK1A | |
| SCHEMBL13051122 | 0.78 | DYRK1B (0.52) | ABL1EGFRBCRSRCPRKCA | |
| SCHEMBL12723010 | 0.78 | ABL1 (0.55) | ABL1EGFRBCRSRCPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |