Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 4/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30847827 | 0.91 | POLQ (0.38) | POLQ | |
| SCHEMBL30847678 | 0.90 | POLQ (0.43) | POLQDRD2DRD3 | |
| SCHEMBL30847646 | 0.86 | POLQ (0.40) | POLQ | |
| SCHEMBL30847705 | 0.85 | POLQ (0.41) | POLQ | |
| SCHEMBL30847706 | 0.85 | POLQ (0.41) | POLQ | |
| SCHEMBL30847711 | 0.85 | POLQ (0.41) | POLQ | |
| SCHEMBL30847713 | 0.84 | POLQ (0.41) | POLQDRD2DRD3 | |
| SCHEMBL30847772 | 0.84 | POLQ (0.38) | POLQDRD2DRD3 | |
| SCHEMBL30847636 | 0.83 | POLQ (0.40) | POLQ | |
| SCHEMBL30847785 | 0.83 | POLQ (0.40) | POLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598901-A1 | PYRROLIDINE AND IMIDAZOLIDINE BASED DNA POLYMERASE THETA INHIBITORS AND USE THEREOF | Thomas Jefferson University (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076964-A1 | PYRROLIDINE AND IMIDAZOLIDINE BASED DNA POLYMERASE THETA INHIBITORS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-04-11 | — | — | WO | disclosed |