Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PER2 | O15055 | 5/20 | 0.35 |
| ▸ | CRY2 | Q49AN0 | 5/20 | 0.35 |
| ▸ | POLQ | O75417 | 5/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 4/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
| ▸ | UBE2M | P61081 | 1/20 | 0.31 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30847627 | 0.81 | POLQ (0.38) | PER2CRY2POLQP2RX7SCN9A | |
| SCHEMBL30847578 | 0.79 | POLQ (0.40) | PER2CRY2POLQ | |
| SCHEMBL30847557 | 0.79 | POLQ (0.40) | PER2CRY2POLQ | |
| SCHEMBL30847785 | 0.79 | POLQ (0.40) | PER2CRY2POLQ | |
| SCHEMBL30847687 | 0.72 | POLQ (0.37) | PER2CRY2POLQSCN9A | |
| SCHEMBL30847786 | 0.72 | POLQ (0.39) | PER2CRY2POLQP2RX7SCN9A | |
| SCHEMBL30847719 | 0.71 | TACR1 (0.38) | P2RX7 | |
| SCHEMBL30847718 | 0.69 | POLQ (0.39) | PER2CRY2POLQ | |
| SCHEMBL30847625 | 0.66 | POLQ (0.54) | POLQ | |
| SCHEMBL30847713 | 0.66 | POLQ (0.41) | POLQP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598901-A1 | PYRROLIDINE AND IMIDAZOLIDINE BASED DNA POLYMERASE THETA INHIBITORS AND USE THEREOF | Thomas Jefferson University (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076964-A1 | PYRROLIDINE AND IMIDAZOLIDINE BASED DNA POLYMERASE THETA INHIBITORS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-04-11 | — | — | WO | disclosed |