Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLQ | O75417 | 4/20 | 0.42 |
| ▸ | TACR1 | P25103 | 7/20 | 0.34 |
| ▸ | CMA1 | P23946 | 2/20 | 0.33 |
| ▸ | LIPE | Q05469 | 5/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.33 |
| ▸ | TACR2 | P21452 | 4/20 | 0.33 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30847696 | 0.91 | POLQ (0.36) | POLQTACR1LIPESLC6A4MGAT2 | |
| SCHEMBL30847768 | 0.90 | POLQ (0.40) | POLQTACR1CMA1LIPE | |
| SCHEMBL30847750 | 0.89 | LIPE (0.34) | POLQCMA1LIPE | |
| SCHEMBL30847823 | 0.87 | TACR1 (0.43) | POLQTACR1CMA1SLC6A4MGAT2 | |
| SCHEMBL30847699 | 0.86 | TACR3 (0.34) | POLQTACR1CMA1TACR2TACR3 | |
| SCHEMBL30847774 | 0.86 | POLQ (0.41) | POLQTACR1LIPE | |
| SCHEMBL30847612 | 0.84 | POLQ (0.40) | POLQTACR1LIPETACR2 | |
| SCHEMBL30847614 | 0.84 | POLQ (0.40) | POLQTACR1LIPESLC6A4TACR2 | |
| SCHEMBL30847709 | 0.84 | POLQ (0.41) | POLQTACR1LIPE | |
| SCHEMBL30847649 | 0.83 | CMA1 (0.35) | POLQCMA1MGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598901-A1 | PYRROLIDINE AND IMIDAZOLIDINE BASED DNA POLYMERASE THETA INHIBITORS AND USE THEREOF | Thomas Jefferson University (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076964-A1 | PYRROLIDINE AND IMIDAZOLIDINE BASED DNA POLYMERASE THETA INHIBITORS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-04-11 | — | — | WO | disclosed |