Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 4/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 2/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27132785 | 1.00 | OXTR (0.39) | OXTRAVPR1ASLC40A1KDM4EALDH1A1 | |
| SCHEMBL27133357 | 0.91 | OXTR (0.37) | OXTRAVPR1ASLC40A1KDM4EALDH1A1 | |
| SCHEMBL30847918 | 0.91 | OXTR (0.37) | OXTRAVPR1ASLC40A1KDM4EALDH1A1 | |
| SCHEMBL30848101 | 0.90 | SCN9A (0.39) | SLC40A1CYP2D6PSEN1PSEN2APH1B | |
| SCHEMBL27132349 | 0.90 | SCN9A (0.39) | SLC40A1CYP2D6PSEN1PSEN2APH1B | |
| SCHEMBL27132955 | 0.90 | MCL1 (0.38) | OXTRAVPR1ASLC40A1KDM4EALDH1A1 | |
| SCHEMBL27142081 | 0.90 | KDM4E (0.37) | OXTRAVPR1ASLC40A1KDM4EALDH1A1 | |
| SCHEMBL30847762 | 0.90 | KDM4E (0.37) | OXTRAVPR1ASLC40A1KDM4EALDH1A1 | |
| SCHEMBL30848059 | 0.90 | MCL1 (0.38) | OXTRAVPR1ASLC40A1KDM4EALDH1A1 | |
| SCHEMBL27143367 | 0.90 | OXTR (0.35) | OXTRAVPR1ASLC40A1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4577536-A1 | PYRAZOLYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY | Hotspot Therapeutics, Inc. (US) | 2025-07-02 | — | — | EP | disclosed |
| WO-2024044730-A1 | PYRAZOLYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY | HOTSPOT THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |