Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 11/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.34 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 1/20 | 0.34 |
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CCR9 | P51686 | 1/20 | 0.34 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | DDX3X | O00571 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27132412 | 1.00 | SLC40A1 (0.41) | SLC40A1PTPN11GLO1AGTR1PAX8 | |
| SCHEMBL27133421 | 0.85 | SLC40A1 (0.44) | SLC40A1PTPN11GLO1CCR9CLK1 | |
| SCHEMBL27133773 | 0.85 | SLC40A1 (0.37) | SLC40A1PTPN11CLK1DDX3X | |
| SCHEMBL30847799 | 0.85 | SLC40A1 (0.37) | SLC40A1PTPN11CLK1DDX3X | |
| SCHEMBL30848094 | 0.85 | SLC40A1 (0.44) | SLC40A1PTPN11GLO1CCR9CLK1 | |
| SCHEMBL27132411 | 0.85 | SLC40A1 (0.38) | SLC40A1PTPN11DDX3X | |
| SCHEMBL27213647 | 0.84 | SLC40A1 (0.40) | SLC40A1PTPN11CLK1 | |
| SCHEMBL30847992 | 0.84 | SLC40A1 (0.40) | SLC40A1PTPN11CLK1 | |
| SCHEMBL30847830 | 0.84 | PTPN11 (0.40) | SLC40A1PTPN11CCR9 | |
| SCHEMBL27139332 | 0.84 | PTPN11 (0.40) | SLC40A1PTPN11CCR9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4577536-A1 | PYRAZOLYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY | Hotspot Therapeutics, Inc. (US) | 2025-07-02 | — | — | EP | disclosed |
| WO-2024044730-A1 | PYRAZOLYLSULFONAMIDE COMPOUNDS AND THEIR USE IN THERAPY | HOTSPOT THERAPEUTICS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |