Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.46 |
| ▸ | THRA | P10827 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | TPMT | P51580 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | SELL | P14151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172086 | 1.00 | TTR (0.46) | TTRTHRATHRBTPMTLMNA | |
| SCHEMBL30848134 | 0.85 | TSHR (0.41) | HTTALDH1A1DPP4SMN1; SMN2HDAC1 | |
| SCHEMBL29171955 | 0.85 | TSHR (0.41) | HTTALDH1A1DPP4SMN1; SMN2HDAC1 | |
| SCHEMBL30848416 | 0.82 | ERN1 (0.34) | HTTALDH1A1HPGDSMN1; SMN2HDAC1 | |
| SCHEMBL29171972 | 0.82 | NOTUM (0.44) | LMNACA12CA1CA2CA7 | |
| SCHEMBL23834717 | 0.76 | KMT2A (0.36) | HTTALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL29921092 | 0.76 | KMT2A (0.36) | HTTALDH1A1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL30848118 | 0.76 | TTR (0.42) | TTRTHRATHRBTPMTLMNA | |
| SCHEMBL22468519 | 0.74 | TTR (0.52) | TTRTHRATHRBTPMTLMNA | |
| SCHEMBL30389602 | 0.74 | TTR (0.52) | TTRTHRATHRBTPMTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720472-A | Benzimidazole compound, and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2024-03-19 | — | — | CN | disclosed |