Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.37 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | CES2 | O00748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29171955 | 1.00 | TSHR (0.41) | TSHRAPOBEC3AHTTAPOBEC3GNCOA1 | |
| SCHEMBL29172086 | 0.85 | TTR (0.46) | HTTALDH1A1SMN1; SMN2KMT2ADPP4 | |
| SCHEMBL30848115 | 0.85 | TTR (0.46) | HTTALDH1A1SMN1; SMN2KMT2ADPP4 | |
| SCHEMBL29171972 | 0.81 | NOTUM (0.44) | ALDH1A1MEN1KMT2APTPN11 | |
| SCHEMBL30848416 | 0.81 | ERN1 (0.34) | HTTALDH1A1SMN1; SMN2KMT2AHDAC1 | |
| SCHEMBL19105527 | 0.78 | PARP1 (0.39) | TSHRAPOBEC3AHTTAPOBEC3GSMN1; SMN2 | |
| SCHEMBL29172088 | 0.76 | HTT (0.39) | TSHRAPOBEC3AHTTAPOBEC3GNCOA1 | |
| SCHEMBL30848072 | 0.76 | HTT (0.39) | TSHRAPOBEC3AHTTAPOBEC3GNCOA1 | |
| SCHEMBL23834717 | 0.74 | KMT2A (0.36) | HTTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL29921092 | 0.74 | KMT2A (0.36) | HTTALDH1A1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720472-A | Benzimidazole compound, and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2024-03-19 | — | — | CN | disclosed |