Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | STING1 | Q86WV6 | 4/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29171993 | 1.00 | HTT (0.40) | HTTTSHRAPOBEC3AAPOBEC3GSTING1 | |
| SCHEMBL30848312 | 0.84 | TTR (0.48) | HTTTSHRSTING1ALDH1A1SMN1; SMN2 | |
| SCHEMBL29172048 | 0.84 | TTR (0.48) | HTTTSHRSTING1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30848123 | 0.78 | ERN1 (0.35) | HTTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29172046 | 0.78 | NOTUM (0.45) | ALDH1A1SMN1; SMN2KDM4ELMNAPOLB | |
| SCHEMBL15020381 | 0.77 | CES2 (0.46) | HTTTSHRAPOBEC3AAPOBEC3GSTING1 | |
| SCHEMBL23111999 | 0.76 | TTR (0.47) | HTTTSHRAPOBEC3AAPOBEC3GNCOA1 | |
| SCHEMBL1854573 | 0.75 | TSHR (0.46) | HTTTSHRAPOBEC3AAPOBEC3GNCOA1 | |
| SCHEMBL29172047 | 0.75 | HTT (0.37) | HTTTSHRAPOBEC3AAPOBEC3GSTING1 | |
| SCHEMBL30848232 | 0.75 | HTT (0.37) | HTTTSHRAPOBEC3AAPOBEC3GSTING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720472-A | Benzimidazole compound, and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2024-03-19 | — | — | CN | disclosed |