Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.74 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.74 |
| ▸ | MAPT | P10636 | 5/20 | 0.74 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.74 |
| ▸ | HPGD | P15428 | 4/20 | 0.74 |
| ▸ | TP53 | P04637 | 3/20 | 0.74 |
| ▸ | MEN1 | O00255 | 4/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.73 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.73 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | GLA | P06280 | 1/20 | 0.71 |
| ▸ | THRB | P10828 | 1/20 | 0.71 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.69 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2481955 | 1.00 | AR (0.75) | ARALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL3819575 | 0.88 | CYP1B1 (0.75) | ARALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL10432745 | 0.88 | CYP3A4 (0.66) | ARALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL9137273 | 0.86 | AR (0.80) | ARALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL3825575 | 0.86 | AR (0.80) | ARALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL7603117 | 0.86 | AR (1.00) | ARALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL3820249 | 0.86 | ALDH1A1 (0.74) | ARALDH1A1KDM4ECYP3A4MAPT | |
| SCHEMBL1629391 | 0.85 | ALDH1A1 (1.00) | ARALDH1A1KDM4ECYP3A4MAPT | |
| Tetramethylluteolin SCHEMBL29572571 | 0.84 | ABCB1 (0.80) | ALDH1A1KDM4ECYP3A4MAPTHSD17B10 | |
| SCHEMBL4649207 | 0.84 | KDM4E (1.00) | ARALDH1A1KDM4ECYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250082602-A1 | OPHTHALMIC COMPOSITION CONTAINING RECOFLAVONE FOR THE TREATMENT OF DRY EYE DISEASE | GL PHARMTECH CORP. (KR) | 2025-03-13 | — | — | US | disclosed |
| CN-117794515-A | Eye drop composition comprising releavance flavone for treating dry eye syndrome and method for preparing the same | 格里医药科技公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117794514-A | Eye drop composition comprising a releaf flavonoid for treating dry eye | 格里医药科技公司 | 2024-03-29 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250082602-A1 | OPHTHALMIC COMPOSITION CONTAINING RECOFLAVONE FOR THE TREATMENT OF DRY EYE DISEASE | NR1H4, NR1H2, NR1H3 | AR 3560/4885ALDH1A1 3395/4885KDM4E 1995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.