Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | GALR2 | O43603 | 1/20 | 0.55 |
| ▸ | MITF | O75030 | 1/20 | 0.55 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | CCR6 | P51684 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14677034 | 1.00 | KMT2A (0.66) | KMT2ALMNAALDH1A1POLBNPSR1 | |
| SCHEMBL14684993 | 0.89 | KMT2A (0.51) | KMT2ALMNAALDH1A1POLBNPSR1 | |
| SCHEMBL3587344 | 0.88 | KMT2A (0.56) | KMT2ALMNAALDH1A1POLBNPSR1 | |
| SCHEMBL30224761 | 0.88 | KMT2A (0.53) | KMT2ALMNAALDH1A1POLBNPSR1 | |
| SCHEMBL13536801 | 0.84 | NPSR1 (0.59) | KMT2ALMNAALDH1A1POLBNPSR1 | |
| SCHEMBL31287241 | 0.83 | NPSR1 (0.58) | KMT2ALMNAALDH1A1POLBNPSR1 | |
| SCHEMBL3850700 | 0.83 | KMT2A (0.65) | KMT2ALMNAALDH1A1POLBNPSR1 | |
| SCHEMBL25400422 | 0.81 | LMNA (0.65) | KMT2ALMNAALDH1A1POLBMAPT | |
| SCHEMBL4018126 | 0.81 | KMT2A (0.60) | KMT2ALMNAALDH1A1POLBNPSR1 | |
| SCHEMBL14677010 | 0.81 | KMT2A (0.48) | KMT2ALMNAALDH1A1POLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118742550-A | Methionine adenosyltransferase inhibitor, preparation method and application thereof | 赛诺哈勃药业（成都）有限公司 | 2024-10-01 | — | — | CN | disclosed |
| CN-117794917-A | Novel indole derivatives, pharmaceutical compositions containing the same and uses thereof | 水疗免疫疗法有限公司 | 2024-03-29 | — | — | CN | disclosed |