Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 4/20 | 0.61 |
| ▸ | CACNA1H | O95180 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | CCR5 | P51681 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30849341 | 0.93 | CACNA1G (0.71) | CACNA1GCACNA1HCYP3A4CYP2D6OPRM1 | |
| SCHEMBL24709329 | 0.93 | CACNA1G (0.71) | CACNA1GCACNA1HCYP3A4CYP2D6OPRM1 | |
| SCHEMBL27194844 | 0.92 | CACNA1G (0.69) | CACNA1GCACNA1HCYP3A4CYP2D6OPRM1 | |
| SCHEMBL27194851 | 0.91 | CACNA1G (0.61) | CACNA1GCACNA1HCYP3A4CYP2D6MEN1 | |
| SCHEMBL24708702 | 0.91 | CACNA1G (0.58) | CACNA1GCACNA1HCYP3A4MEN1KMT2A | |
| SCHEMBL24709344 | 0.91 | CACNA1G (0.58) | CACNA1GCACNA1HCYP3A4MEN1KMT2A | |
| SCHEMBL24709345 | 0.90 | CACNA1G (0.66) | CACNA1GCACNA1HCYP3A4CYP2D6OPRM1 | |
| SCHEMBL30849340 | 0.90 | CACNA1G (0.66) | CACNA1GCACNA1HCYP3A4CYP2D6OPRM1 | |
| SCHEMBL27194842 | 0.88 | CACNA1G (0.54) | CACNA1GCACNA1HCYP3A4CYP2D6OPRM1 | |
| SCHEMBL4703256 | 0.86 | CACNA1G (0.52) | CACNA1GCACNA1HCYP3A4CYP2D6OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4353713-A1 | T-TYPE CALCIUM CHANNEL BLOCKER | Kinki University (JP) | 2024-04-17 | — | — | EP | disclosed |