Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 15/20 | 0.40 |
| ▸ | PPARA | Q07869 | 10/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.38 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14212038 | 0.82 | PPARD (0.40) | PPARDPPARAFFAR1 | |
| SCHEMBL10011208 | 0.82 | PPARD (0.40) | PPARDPPARAFFAR1 | |
| SCHEMBL14212036 | 0.82 | PPARD (0.40) | PPARDPPARAFFAR1 | |
| SCHEMBL14234058 | 0.75 | PPARD (0.57) | PPARDPPARA | |
| SCHEMBL14212057 | 0.74 | FFAR1 (0.40) | PPARDPPARAFFAR1PPARG | |
| SCHEMBL14212047 | 0.74 | FFAR1 (0.51) | PPARDPPARAFFAR1 | |
| SCHEMBL19839279 | 0.73 | PPARD (0.44) | PPARDPPARAFFAR1 | |
| SCHEMBL4077603 | 0.73 | FFAR1 (0.60) | PPARDPPARAFFAR1PPARG | |
| SCHEMBL30849377 | 0.73 | EPAS1 (0.40) | — | |
| SCHEMBL30849375 | 0.73 | EPAS1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800949-A | Pyrimidine-containing polycyclic derivative, preparation method and application thereof | 江苏豪森药业集团有限公司 | 2024-04-02 | — | — | CN | disclosed |