Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.31 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.31 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.31 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12938791 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2CYP2D6CYP2C19GBA1CARM1 | |
| SCHEMBL18542747 | 1.00 | SMN1; SMN2 (0.39) | SMN1; SMN2CYP2D6CYP2C19GBA1CARM1 | |
| SCHEMBL19062831 | 0.87 | SMN1; SMN2 (0.48) | SMN1; SMN2CARM1PRMT6PRMT1PRMT8 | |
| SCHEMBL17919049 | 0.81 | DRD2 (0.41) | — | |
| SCHEMBL21120720 | 0.81 | DRD2 (0.41) | — | |
| SCHEMBL19807234 | 0.81 | DRD2 (0.41) | — | |
| SCHEMBL18007363 | 0.81 | DRD2 (0.41) | — | |
| SCHEMBL19799037 | 0.81 | DRD2 (0.41) | — | |
| SCHEMBL19799064 | 0.81 | DRD2 (0.41) | — | |
| SCHEMBL13900662 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800975-A | Compounds with anti-KRAS mutant tumor activity | 泰励生物科技（上海）有限公司 | 2024-04-02 | — | — | CN | disclosed |