Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 3/20 | 0.54 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.54 |
| ▸ | PPARG | P37231 | 2/20 | 0.54 |
| ▸ | HTR2B | P41595 | 2/20 | 0.54 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.54 |
| ▸ | NAE1 | Q13564 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21083620 | 1.00 | AGTR2 (0.54) | AGTR2AGTR1CYP3A4ADORA3ADRA2B | |
| SCHEMBL3976108 | 0.92 | AGTR2 (0.56) | AGTR2AGTR1CYP3A4ADORA3ADRA2B | |
| SCHEMBL30951659 | 0.92 | AGTR2 (0.56) | AGTR2AGTR1CYP3A4ADORA3ADRA2B | |
| SCHEMBL21083849 | 0.92 | AGTR2 (0.49) | AGTR2AGTR1CYP3A4ADORA3ADRA2B | |
| SCHEMBL21083523 | 0.91 | NAE1 (0.52) | AGTR2AGTR1CYP3A4ADORA3ADRA2B | |
| SCHEMBL21083883 | 0.91 | AGTR2 (0.48) | AGTR2AGTR1CYP3A4ADORA3ADRA2B | |
| SCHEMBL30849982 | 0.91 | AGTR2 (0.48) | AGTR2AGTR1CYP3A4ADORA3ADRA2B | |
| SCHEMBL21083570 | 0.91 | AGTR2 (0.51) | AGTR2AGTR1CYP3A4ADORA3ADRA2B | |
| SCHEMBL21083925 | 0.90 | AGTR2 (0.50) | AGTR2AGTR1CYP3A4ADORA3ADRA2B | |
| SCHEMBL21083933 | 0.90 | AGTR2 (0.58) | AGTR2AGTR1CYP3A4ADORA3ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3478672-B1 | BIARYLMETHYL HETEROCYCLES | UNIV MONTREAL (CA) | 2024-04-10 | — | — | EP | disclosed |