Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.47 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 6/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
| ▸ | RELA | Q04206 | 1/20 | 0.46 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23971161 | 1.00 | KDM4E (0.47) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL26606605 | 0.88 | KDM4E (0.53) | KDM4EALDH1A1MAPTGAAL3MBTL1 | |
| SCHEMBL448918 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL29878715 | 0.83 | KDM4E (0.50) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL30159175 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL23971183 | 0.83 | KDM4E (0.44) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL30273152 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL1727263 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL23970940 | 0.81 | KDM4E (0.51) | KDM4EALDH1A1MAPTHPGDGAA | |
| SCHEMBL23970710 | 0.80 | KDM4E (0.42) | KDM4EALDH1A1MAPTHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115551862-B | Macrocyclic inhibitors of peptidyl arginine deiminase | 吉利德科学公司 | 2024-04-12 | — | — | CN | disclosed |