Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | PDCD1LG2 | Q9BQ51 | 3/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30850156 | 0.86 | METAP1 (0.39) | METAP1NAMPTMAPK1CYP17A1ATR | |
| SCHEMBL30850151 | 0.83 | MAPK1 (0.36) | MAPK1PI4KBAAK1 | |
| SCHEMBL20901331 | 0.82 | METAP1 (0.44) | METAP1NAMPTMAPK1CYP17A1ATR | |
| SCHEMBL30850148 | 0.81 | IDO1 (0.42) | METAP1PDCD1LG2CD274HPGD | |
| SCHEMBL30850169 | 0.77 | METAP1 (0.40) | METAP1NAMPTMAPK1CYP17A1ATR | |
| SCHEMBL7382660 | 0.77 | METAP1 (0.42) | METAP1NAMPTCYP17A1ATRL3MBTL1 | |
| SCHEMBL30450099 | 0.77 | METAP1 (0.42) | METAP1NAMPTCYP17A1ATRL3MBTL1 | |
| SCHEMBL27703346 | 0.75 | METAP1 (0.44) | METAP1NAMPTCYP17A1ATRL3MBTL1 | |
| SCHEMBL32665001 | 0.74 | NPC1 (0.42) | METAP1NAMPTMAPK1ATRL3MBTL1 | |
| SCHEMBL27289163 | 0.74 | NPC1 (0.42) | METAP1NAMPTMAPK1ATRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4605400-A1 | NOVEL TRIHETEROCYCLIC COMPOUNDS | Idience Co., Ltd. (KR) | 2025-08-27 | — | — | EP | disclosed |
| WO-2025076523-A1 | RAS INHIBITORS AND METHODS OF USE THEREOF | KESTREL THERAPEUTICS, INC. (US) | 2025-04-10 | — | — | WO | disclosed |
| WO-2024085661-A1 | NOVEL TRIHETEROCYCLIC COMPOUNDS | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2024-04-25 | — | — | WO | disclosed |