SCHEMBL30850148

SCHEMBL30850148

CC(NCCO)c1ccccc1NC(=O)OC(C)(C)C

nearest known ligand 0.42

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 1/20 0.42
TP53 P04637 1/20 0.41
MAPT P10636 1/20 0.41
NLRP3 Q96P20 1/20 0.41
ELANE P08246 1/20 0.39
CTRB1 P17538 1/20 0.39
RXFP1 Q9HBX9 1/20 0.39
LMNA P02545 1/20 0.39
POLB P06746 1/20 0.39
BRD9 Q9H8M2 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
GPR139 Q6DWJ6 1/20 0.38
MALT1 Q9UDY8 1/20 0.37
PDCD1LG2 Q9BQ51 2/20 0.37
CD274 Q9NZQ7 2/20 0.37
METAP1 P53582 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24166675 0.82 IDO1 (0.43) IDO1TP53MAPTNLRP3ELANE
SCHEMBL7419310 0.81 IDO1 (0.45) IDO1TP53MAPTNLRP3ELANE
SCHEMBL11254091 0.81 TSHR (0.45) NLRP3LMNAPOLBHPGDSMN1; SMN2
SCHEMBL30850160 0.81 METAP1 (0.39) HPGDPDCD1LG2CD274METAP1
SCHEMBL2737224 0.81 NLRP3 (0.56) IDO1TP53MAPTNLRP3RXFP1
SCHEMBL8837511 0.80 CXCL8 (0.49) IDO1TP53MAPTNLRP3ELANE
SCHEMBL8214432 0.80 IDO1 (0.43) IDO1TP53MAPTNLRP3ELANE
SCHEMBL1951665 0.80 CXCL8 (0.49) IDO1TP53MAPTNLRP3ELANE
SCHEMBL1951582 0.80 CXCL8 (0.49) IDO1TP53MAPTNLRP3ELANE
SCHEMBL1771858 0.79 IDO1 (0.47) IDO1TP53MAPTNLRP3ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4605400-A1 NOVEL TRIHETEROCYCLIC COMPOUNDS Idience Co., Ltd. (KR) 2025-08-27 EP disclosed
WO-2024085661-A1 NOVEL TRIHETEROCYCLIC COMPOUNDS ILDONG PHARMACEUTICAL CO., LTD. (KR) 2024-04-25 WO disclosed