SCHEMBL30850671

SCHEMBL30850671

Nc1ccc(Nc2ccc(O)c3c2C(=O)c2ccccc2C3=O)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.67
KMT2A Q03164 4/20 0.67
MAPT P10636 4/20 0.67
TDP1 Q9NUW8 3/20 0.67
LMNA P02545 3/20 0.67
MAPK1 P28482 3/20 0.67
NPSR1 Q6W5P4 2/20 0.67
L3MBTL1 Q9Y468 2/20 0.67
RAB9A P51151 2/20 0.67
NPC1 O15118 1/20 0.67
PRKCA P17252 2/20 0.59
GNG2 P59768 3/20 0.59
GNB1 P62873 3/20 0.59
MAOA P21397 1/20 0.56
POLB P06746 3/20 0.55
MCL1 Q07820 2/20 0.55
PABPC1 P11940 1/20 0.55
HPGD P15428 1/20 0.55
CSNK1A1 P48729 1/20 0.55
CSNK1D P48730 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10810281 1.00 MEN1 (0.67) MEN1KMT2AMAPTTDP1LMNA
SCHEMBL14413914 0.92 MEN1 (0.70) MEN1KMT2AMAPTTDP1LMNA
SCHEMBL14413350 0.92 MEN1 (0.59) MEN1KMT2AMAPTTDP1LMNA
SCHEMBL11872441 0.91 GNG2 (0.63) MEN1KMT2AMAPTTDP1LMNA
SCHEMBL11803749 0.89 MAPT (0.52) MEN1KMT2AMAPTTDP1LMNA
SCHEMBL11806707 0.89 MAPT (0.52) MEN1KMT2AMAPTTDP1LMNA
SCHEMBL14413898 0.89 MEN1 (0.56) MEN1KMT2AMAPTTDP1LMNA
SCHEMBL5273789 0.88 MAPT (0.71) MEN1KMT2AMAPTTDP1LMNA
SCHEMBL29500408 0.88 MEN1 (0.70) MEN1KMT2AMAPTTDP1LMNA
SCHEMBL341146 0.88 MEN1 (0.70) MEN1KMT2AMAPTTDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117777755-A Reactive dye containing siloxane group and preparation method thereof 大连理工大学 2024-03-29 CN disclosed