Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5471696 | 1.00 | HTR2C (0.57) | HTR2CMEN1POLBKMT2AMAPK1 | |
| SCHEMBL8253641 | 0.90 | HTR2C (0.50) | HTR2CMAP3K12 | |
| Hydrochloric Acid SCHEMBL31500114 | 0.89 | HTR2C (0.51) | HTR2CMAP3K12 | |
| SCHEMBL16452781 | 0.88 | KMT2A (0.42) | HTR2CKMT2A | |
| SCHEMBL29852305 | 0.88 | KMT2A (0.42) | HTR2CKMT2A | |
| Hydrochloric Acid SCHEMBL23211937 | 0.86 | HTR2C (0.47) | HTR2CMEN1POLBKMT2AMAPK1 | |
| SCHEMBL28131310 | 0.84 | ALOX5AP (0.43) | HTR2CKMT2A | |
| SCHEMBL16452775 | 0.84 | PPARD (0.40) | HTR2CKMT2A | |
| SCHEMBL17729510 | 0.83 | CHRNB2 (0.49) | HTR2CKMT2A | |
| SCHEMBL25647216 | 0.83 | PPARD (0.42) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642393-A | Novel PARP7 inhibitor and application thereof | 上海齐鲁制药研究中心有限公司 | 2024-03-01 | — | — | CN | disclosed |