Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | IGF1R | P08069 | 1/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | TYK2 | P29597 | 1/20 | 0.43 |
| ▸ | JAK3 | P52333 | 1/20 | 0.43 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | HPGDS | O60760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30852111 | 0.84 | KDM4E (0.48) | KDM4EMAPTTHRBIGF1RGPR119 | |
| SCHEMBL27312564 | 0.84 | KDM4E (0.48) | KDM4EMAPTTHRBIGF1RGPR119 | |
| SCHEMBL30851603 | 0.84 | KDM4E (0.48) | KDM4EMAPTTHRBIGF1RGPR119 | |
| SCHEMBL30851691 | 0.82 | KDM4E (0.48) | KDM4EMAPTTHRBIGF1RGPR119 | |
| SCHEMBL30852105 | 0.82 | KDM4E (0.46) | KDM4EMAPTTHRBIGF1RGPR119 | |
| SCHEMBL27313057 | 0.82 | KDM4E (0.46) | KDM4EMAPTTHRBIGF1RGPR119 | |
| SCHEMBL30852127 | 0.80 | KDM4E (0.48) | KDM4EMAPTTHRBGPR119PTPN2 | |
| SCHEMBL23748832 | 0.80 | KDM4E (0.52) | KDM4EMAPTTHRBGPR119NAMPT | |
| SCHEMBL30851610 | 0.79 | KDM4E (0.45) | KDM4EMAPTTHRBGPR119JAK2 | |
| SCHEMBL30851897 | 0.79 | MAPT (0.45) | KDM4EMAPTTHRBGPR119ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587014-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | Vanqua Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059096-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |