Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.42 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27313079 | 1.00 | MAPT (0.45) | MAPTKDM4ETHRBHPGDMEN1 | |
| SCHEMBL30851603 | 0.86 | KDM4E (0.48) | MAPTKDM4ETHRBHPGDMEN1 | |
| SCHEMBL30852105 | 0.84 | KDM4E (0.46) | MAPTKDM4ETHRBHPGDMEN1 | |
| SCHEMBL27313057 | 0.84 | KDM4E (0.46) | MAPTKDM4ETHRBHPGDMEN1 | |
| SCHEMBL30851610 | 0.83 | KDM4E (0.45) | MAPTKDM4ETHRBDDB1CRBN | |
| SCHEMBL27313047 | 0.83 | KDM4E (0.45) | MAPTKDM4ETHRBDDB1CRBN | |
| SCHEMBL30852127 | 0.82 | KDM4E (0.48) | MAPTKDM4ETHRBHPGDMEN1 | |
| SCHEMBL30851884 | 0.79 | KDM4E (0.49) | MAPTKDM4ETHRBHPGDALDH1A1 | |
| SCHEMBL27313118 | 0.79 | KDM4E (0.45) | MAPTKDM4ETHRBHPGDMEN1 | |
| SCHEMBL30851691 | 0.79 | KDM4E (0.48) | MAPTKDM4ETHRBHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587014-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | Vanqua Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059096-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |