Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.41 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | CTSE | P14091 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.40 |
| ▸ | SRC | P12931 | 1/20 | 0.40 |
| ▸ | ADK | P55263 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30851996 | 0.81 | GPR119 (0.47) | GPR119ADK | |
| SCHEMBL16078096 | 0.77 | MAP4K4 (0.44) | GPR119SRCADKMAP4K4 | |
| SCHEMBL16049455 | 0.76 | MAP4K4 (0.44) | GPR119SRCADKMAP4K4 | |
| SCHEMBL26641481 | 0.75 | GPR119 (0.45) | GPR119PIK3CAADK | |
| SCHEMBL30490329 | 0.75 | GPR119 (0.45) | GPR119PIK3CAADK | |
| SCHEMBL30785488 | 0.75 | GPR119 (0.42) | GPR119ADKMAP4K4 | |
| SCHEMBL25939124 | 0.75 | GPR119 (0.42) | GPR119 | |
| SCHEMBL30785450 | 0.75 | GPR119 (0.42) | GPR119ADKMAP4K4 | |
| SCHEMBL31605021 | 0.75 | GPR119 (0.42) | GPR119ALDH1A1ADK | |
| SCHEMBL27158067 | 0.75 | GPR119 (0.42) | GPR119ADKMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587014-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | Vanqua Bio, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059096-A2 | C5AR1 ANTAGONISTS AND USES THEREOF | VANQUA BIO, INC. (US) | 2024-03-21 | — | — | WO | disclosed |