Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HPGD | P15428 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.43 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | CASP1 | P29466 | 4/20 | 0.43 |
| ▸ | CASP7 | P55210 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5085565 | 0.78 | HSD17B3 (0.57) | RXFP1LMNANPSR1MAPTESR2 | |
| SCHEMBL9211053 | 0.71 | MCL1 (0.63) | RXFP1LMNAPPARGNCOA2NPSR1 | |
| SCHEMBL972802 | 0.70 | KDM4E (0.67) | RXFP1LMNAPPARGNCOA2NPSR1 | |
| SCHEMBL2226799 | 0.69 | ESR2 (0.57) | RXFP1LMNANPSR1MAPTESR2 | |
| Hydrochloric Acid SCHEMBL11055257 | 0.69 | TP53 (0.49) | RXFP1LMNAPPARGNCOA2NPSR1 | |
| SCHEMBL10744925 | 0.69 | HSD17B3 (0.62) | RXFP1LMNAPPARGNCOA2NPSR1 | |
| SCHEMBL11484411 | 0.69 | NQO1 (0.52) | MCL1KDM4EALDH1A1HPGDHSD17B10 | |
| Hydrochloric Acid SCHEMBL11086666 | 0.69 | TP53 (0.48) | RXFP1LMNAPPARGNCOA2NPSR1 | |
| SCHEMBL5649508 | 0.68 | TP53 (0.53) | RXFP1LMNAPPARGNCOA2NPSR1 | |
| SCHEMBL10743963 | 0.68 | GPR35 (0.76) | RXFP1LMNAPPARGNCOA2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9677115-B2 | Enzyme substrates for visualizing acidic organelles | MARKER GENE TECHNOLOGIES, INC. (US) | 2017-06-13 | — | — | US | disclosed |
| US-20130252268-A1 | Enzyme substrates for visualizing acidic organelles | MARKER GENE TECHNOLOGIES, INC. (US) | 2013-09-26 | — | — | US | disclosed |
| US-8460862-B2 | Enzyme substrates for visualizing acidic organelles | Marker Gene Technologies (US) | 2013-06-11 | — | — | US | disclosed |
| US-20100233744-A1 | Enzyme substrates for visualizing acidic organelles | MARKER GENE TECHNOLOGIES, INC. | 2010-09-16 | — | — | US | disclosed |