SCHEMBL3085257

SCHEMBL3085257

CCCCC(O)(CO)OC(=O)c1ccc(C(=O)O)cc1

nearest known ligand 0.44

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.44
TSHR P16473 1/20 0.44
PLA2G4B P0C869 4/20 0.43
MAPT P10636 2/20 0.43
ALDH1A1 P00352 2/20 0.42
RARB P10826 10/20 0.42
MEN1 O00255 1/20 0.40
RARA P10276 1/20 0.40
MTOR P42345 1/20 0.40
KMT2A Q03164 1/20 0.40
PLA2G4A P47712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3085256 0.94 LMNA (0.42) TSHRMAPTALDH1A1KMT2A
SCHEMBL3098902 0.90 TP53 (0.43) TP53TSHRPLA2G4BMAPTALDH1A1
SCHEMBL3087841 0.86 KMT2A (0.43) TP53TSHRPLA2G4BKMT2A
SCHEMBL3087840 0.82 SMN1; SMN2 (0.42) ALDH1A1
SCHEMBL3093189 0.79 MAPT (0.45) TP53TSHRPLA2G4BMAPTALDH1A1
SCHEMBL3080380 0.77 KMT2A (0.42) TP53TSHRPLA2G4BKMT2A
SCHEMBL1648606 0.76 MAPT (0.49) TP53TSHRPLA2G4BMAPTALDH1A1
SCHEMBL18817713 0.76 TP53 (0.54) TP53TSHRPLA2G4BMAPTALDH1A1
SCHEMBL28581476 0.75 TP53 (0.43) TP53TSHRPLA2G4BMAPTALDH1A1
SCHEMBL690294 0.75 TP53 (0.49) TP53TSHRPLA2G4BMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7799892-B2 Method of making polybutylene terephthalate and compositions and articles comprising the same SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-09-21 US claimed
US-20090275698-A1 Method of Making Polybutylene Terephthalate and Compositions and Articles Comprising the Same SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-11-05 US claimed
US-7799892-B2 Method of making polybutylene terephthalate and compositions and articles comprising the same SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-09-21 US disclosed
US-7799892-B2 Method of making polybutylene terephthalate and compositions and articles comprising the same SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2010-09-21 US disclosed
US-20090275698-A1 Method of Making Polybutylene Terephthalate and Compositions and Articles Comprising the Same SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-11-05 US disclosed
US-20090275698-A1 Method of Making Polybutylene Terephthalate and Compositions and Articles Comprising the Same SHPP GLOBAL TECHNOLOGIES B.V. (NL) 2009-11-05 US disclosed