Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 19/20 | 0.70 |
| ▸ | OPRM1 | P35372 | 15/20 | 0.70 |
| ▸ | OPRK1 | P41145 | 12/20 | 0.70 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21179827 | 0.82 | OPRL1 (1.00) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL12084263 | 0.80 | OPRL1 (0.48) | OPRL1OPRM1OPRK1 | |
| SCHEMBL8220230 | 0.80 | OPRL1 (0.55) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL30441418 | 0.80 | OPRM1 (0.60) | OPRL1OPRM1OPRK1 | |
| SCHEMBL30507191 | 0.80 | OPRM1 (0.53) | OPRL1OPRM1OPRK1 | |
| SCHEMBL30507197 | 0.80 | OPRM1 (0.53) | OPRL1OPRM1OPRK1 | |
| SCHEMBL23798683 | 0.79 | OPRL1 (0.59) | OPRL1OPRM1OPRK1 | |
| SCHEMBL23799177 | 0.78 | OPRL1 (0.61) | OPRL1OPRM1OPRK1OPRD1 | |
| SCHEMBL13640931 | 0.77 | OPRM1 (0.59) | OPRL1OPRM1OPRK1 | |
| SCHEMBL12084836 | 0.77 | OPRL1 (0.46) | OPRL1OPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642402-A | Spiropiperidine ring derivative and pharmaceutical composition, preparation method and application thereof | 宜昌人福药业有限责任公司 | 2024-03-01 | — | — | CN | disclosed |