SCHEMBL30853201

SCHEMBL30853201

Fc1ccc(Cl)cc1CBr

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
CYP3A4 P08684 4/20 0.41
HIF1A Q16665 3/20 0.41
HPGD P15428 3/20 0.41
IDO1 P14902 2/20 0.41
MAPT P10636 2/20 0.41
ALOX15 P16050 2/20 0.41
SLC22A1 O15245 1/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
HSP90AA1 P07900 1/20 0.41
HSPD1 P10809 1/20 0.41
HSPA5 P11021 1/20 0.41
ALOX12 P18054 1/20 0.41
CASP1 P29466 1/20 0.41
HTT P42858 1/20 0.41
BLM P54132 1/20 0.41
HSPE1 P61604 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL269490 1.00 MEN1 (0.41) MEN1KMT2ACYP3A4HIF1AHPGD
SCHEMBL19030709 0.98 MEN1 (0.40) MEN1KMT2ACYP3A4HIF1AHPGD
SCHEMBL269324 0.84 HTR2A (0.41) MEN1KMT2ACYP3A4HIF1AHPGD
SCHEMBL20901360 0.82 MEN1 (0.39) MEN1KMT2ACYP3A4HIF1AHPGD
SCHEMBL29448063 0.82 MEN1 (0.39) MEN1KMT2ACYP3A4HIF1AHPGD
SCHEMBL30089455 0.80 IDO1 (0.44) MEN1KMT2ACYP3A4HIF1AHPGD
SCHEMBL384040 0.80 IDO1 (0.44) MEN1KMT2ACYP3A4HIF1AHPGD
SCHEMBL14774649 0.80 HTR2A (0.38) MEN1KMT2ACYP3A4HIF1AHPGD
SCHEMBL80688 0.79 SIRT2 (0.39) MEN1KMT2ACYP3A4HIF1AHPGD
SCHEMBL189771 0.78 TP53 (0.48) MEN1KMT2ACYP3A4HIF1AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4739669-A1 SODIUM CHANNEL BLOCKERS Novartis AG (CH) 2026-05-13 EP disclosed
EP-4587430-A1 PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS Syngenta Crop Protection AG (CH) 2025-07-23 EP disclosed
CN-119816490-A Pesticidally active cyclic amine compounds 先正达农作物保护股份公司 2025-04-11 CN disclosed
WO-2025064534-A1 SUBSTITUTED AMINE COMPOUNDS, COMPOSITIONS AND METHODS OF USE DEEP APPLE THERAPEUTICS, INC. (US) 2025-03-27 WO disclosed
WO-2025011450-A1 SODIUM CHANNEL BLOCKERS NOVARTIS AG (CH) 2025-01-16 WO disclosed
WO-2024056732-A1 PESTICIDALLY ACTIVE CYCLIC AMINE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-03-21 WO disclosed